|NCF Reports on New Marker Found in Patients with
By Alan Cocchetto © 2001
The National CFIDS Foundation is now reporting that myalgic
encephalomyelitis/chronic fatigue syndrome patients are obtaining abnormal test results
for serum chromogranin-A. To our knowledge, this is the first time this finding has been
reported upon for CFS patients.
Chromogranin-A, however, has also been useful in the diagnosis of
diseases associated with alterations in sympathoadrenal activity. Since chromogranin-A is
present in secretory vesicles containing catecholamines and considering the role that
catecholamines play in blood pressure regulation - this is most intriguing in CFS in light
of the current work on neurally mediated hypotension (NMH).
The National CFIDS Foundation encourages CFS patients to discuss the
potential role of celiac disease along with the non-invasive serum chromogranin-A test
with their physicians. Serum chromogranin-A testing is available through Specialty
Labs in California.
Source: Chromogranins: Functional and Clinical Aspects; Plenum Publishers, New York; 2000
[Ed. Note: Specialty Laboratories may be reached, toll-free (in US), at 1-800-421-7110.]
The National CFIDS Foundation* 103 Aletha Rd, Needham Ma 02492 * (781) 449-3535 Fax (781) 449-8606