A high-throughput alpha particle irradiation system for monitoring DNA damage repair, genome instability and screening in human cell and yeast model systems
Authors:
Aaron A. Goodarzi, Darren R. Brenner, Dustin D. Pearson, Fintan K. T. Stanley, Greg Pierce, Hali Morrison, James E. Johnston, Jennifer A. Chan, Jennifer A. Cobb, John M. Danforth, N. Daniel Berger, Nicolas P. Ploquin, Tyler S. Warnock
Date Published:
2021
Relative to low LET photon radiation (X-rays,
gamma rays), higher LET particle radiation produces
more disease-causing, complex DNA damage that
is substantially more challenging to resolve quickly
or accurately.
