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Elevated Neuroactive Progesterone Metabolites in Women with Chronic Fatigue Syndrome
Status: Archived
Authors: a-Missagh Ghandirian, Beverly E. Pearson Murphy, Craig Watts, Cyndie M. Allison
Date Published: 2000
Although some ring A-reduced progesterone metabolites are known to be powerful anesthetics at high doses, and to have anxiolytic or soporific effects at lower doses, their physiological relevance remains unknown. We measure five of these steroids, along with progesterone and its precursor pregnenolone, in 20 women with chronic fatigue syndrome (CFS) and in 13 age-matched control women.
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