STAT1-dependent IgG cell-surface expression in a human B cell line derived from a STAT1-deficient patient

Status: Archived
Authors: Emmanuelle E. Fabre, Falk Nimmerjahn, Georg W. Bornkamm, Imen Najjar, Isabelle Dusanter-Fourt, Pierre Olivier Schischmanoff, Pierre-Antoine Deglesne, Remi Fagard, Stephanie Boisson-Dupuis
Date Published: 2010
Publication: Journal of Leukocyte Biology
STAT1 is a key effector of cytokines involved in the resistance to pathogens; its identified transcriptional targets mediate the innate immune response involved in the defense against viruses and bacteria.