NCF-funded Research

Note:  If you are a CFIDS/ME patient who will be undergoing surgery, you can further research by donating samples taken during surgery.  Click here for more information.

The National CFIDS Foundation has contributed funds towards the following research studies:

Field of study
Ciguatera Toxicology
General
Immunology
Infectious Disease
Neurology
Virology
Other Related Scientific Research Not Directly Funded by the NCF

 Ciguatera Toxicology

• "Chronic phase lipids in sera of chronic fatigue syndrome (CFS), chronic ciguatera fish poisoning (CCFP), hepatitis B, and cancer with antigenic epitope resembling ciguatoxin, as assessed with MAb-CTX." J Clin Lab Anal. (2003)  (PDF file)

• "Chronic phase lipids in sera of several chronic diseases reacting with MAb-CTX (antibody to ciguatoxin)"  Journal of Toxicology: Toxins Review (2003) (PDF file)

• Ciguatera Toxin FAQ  (2003; 2005)

• Ciguatera testing protocol (2003; 2005)

• The Ciguatera Epitope: So What Do We Really Know Thus Far? Forum newsletter (2003)

• Presentation given by Dr. Yoshitsugi Hokama at the International Symposium on Toxins and Natural Products (2002)  (PDF file format)

• Neurotoxin Discovered in Chronic Fatigue Syndrome (Press release: 2002)

• The Neurology of ciguatera (PDF file format or  text-only format).  J Neurol Neurosurg Psychiatry (2001)

General

• Polygenic Contributions of Procoagulant Genetic Factors in
  Chronic Fatigue Syndrome and Related Chronic Illnesses. Genetics in Medicine (2002)

• Activation of the coagulation system in Gulf War Illness: a potential pathophysiologic link with chronic fatigue syndrome. A laboratory approach to diagnosis. Blood Coagul Fibrinolysis (2000)

Immunology

• Dr. Konstance Knox Presents STAT1 Data to
  Researchers and Clinicians at AACFS Conference AACFS Conference (2004)

• STAT1-alpha and p53 Deficiencies Are Found In Patients With Chronic Fatigue Syndrome Forum newsletter (2003)

• Expanded Model for RNase L Fragmentation in CFS Uncovered; The National CFIDS Foundation Announces The Use Of Elastase Inhibitors as a Potential Treatment for CFS Inovations Forum newsletter (2003)

          Click here for the above 2 articles together in printable PDF file format.

• Potential Role of STAT1 in the Pathogenesis of Chronic Fatigue Syndrome Institute for Viral Pathogenesis (2003)

Infectious Disease

• Persistent Active Human Herpesvirus Six (HHV-6) Infections In Patients With Chronic Fatigue Syndrome.  AACFS Conference (1998)

Neurology

• The roles of orthostatic hypotension, orthostatic tachycardia, and subnormal erythrocyte volume in the pathogenesis of the chronic fatigue syndrome Am J Med Sci (2000)
   

• Circulating blood volume in chronic fatigue syndrome Journal of Chronic Fatigue Syndrome (1998)

Virology

• Potential animal (zoonotic) virus identified in patients with Chronic Fatigue Syndrome, Multiple Sclerosis and Epilepsy  (NCF Press Release: 2006) 
  Click here for PDF version.
• Parainfluenza Virus-5: A new paradigm and a serious host challenge  NCF Paper (2006)  
  Click here for the PDF version.
• Potential role of persistent paramyxovirus infection in Chronic Fatigue Syndrome Interim progress report and research proposal (2005)  (PDF file format)

Other Related Scientific Research
Not Directly Funded by the NCF:

• Okadaic acid-like toxin in systemic lupus erythematosus patients: hypothesis for toxin-induced pathology, immune dysregulation, and transactivation of herpesviruses Medical Hypotheses  (1996)
  (PDF file format)

• A chronic fatigue syndrome-related proteome in human cerebrospinal fluid  BMC Neurology (2005)  (PDF file format)

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